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Continuous administration of bevacizumab plus capecitabine, even after acquired resistance to bevacizumab, restored anti-angiogenic and antitumor effect in a human colorectal cancer xenograft model
Vascular endothelial growth factor (VEGF)-neutralizing therapy with bevacizumab has become increasingly important for treating colorectal cancer. It was demonstrated that second-line chemotherapy together with bevacizumab after disease progression (PD) on first-line therapy including bevacizumab sho...
Autores principales: | Iwai, Toshiki, Sugimoto, Masamichi, Harada, Suguru, Yorozu, Keigo, Kurasawa, Mitsue, Yamamoto, Kaname |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933557/ https://www.ncbi.nlm.nih.gov/pubmed/27350037 http://dx.doi.org/10.3892/or.2016.4902 |
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