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Contributions of Counter-Charge in a Potassium Channel Voltage-Sensor Domain
Voltage-sensor domains couple membrane potential to conformational changes in voltage-gated ion channels and phosphatases. Highly co-evolved acidic and aromatic side-chains assist the transfer of cationic side-chains across the transmembrane electric field during voltage-sensing. We investigated the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933587/ https://www.ncbi.nlm.nih.gov/pubmed/21785425 http://dx.doi.org/10.1038/nchembio.622 |