Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age‐related insulin resistance

While age‐related insulin resistance and hyperinsulinemia are usually considered to be secondary to changes in muscle, the liver also plays a key role in whole‐body insulin handling and its role in age‐related changes in insulin homeostasis is largely unknown. Here, we show that patent pores called...

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Detalles Bibliográficos
Autores principales: Mohamad, Mashani, Mitchell, Sarah Jayne, Wu, Lindsay Edward, White, Melanie Yvonne, Cordwell, Stuart James, Mach, John, Solon‐Biet, Samantha Marie, Boyer, Dawn, Nines, Dawn, Das, Abhirup, Catherine Li, Shi‐Yun, Warren, Alessandra, Hilmer, Sarah Nicole, Fraser, Robin, Sinclair, David Andrew, Simpson, Stephen James, de Cabo, Rafael, Le Couteur, David George, Cogger, Victoria Carroll
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933657/
https://www.ncbi.nlm.nih.gov/pubmed/27095270
http://dx.doi.org/10.1111/acel.12481

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