Cargando…
Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats
RATIONALE: Numerous preclinical and clinical studies have reported the rapid and sustained antidepressant effects of the NMDA receptor antagonist ketamine. Because ketamine induces several undesirable and dangerous effects, a variety of strategies have been suggested to avoid such effects. OBJECTIVE...
Autores principales: | Podkowa, Karolina, Pochwat, Bartłomiej, Brański, Piotr, Pilc, Andrzej, Pałucha-Poniewiera, Agnieszka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933730/ https://www.ncbi.nlm.nih.gov/pubmed/27286960 http://dx.doi.org/10.1007/s00213-016-4325-7 |
Ejemplares similares
-
Combined Administration of (R)-Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Induces Rapid and Sustained Effects in the CUMS Model of Depression via a TrkB/BDNF-Dependent Mechanism
por: Rafało-Ulińska, Anna, et al.
Publicado: (2022) -
On the mechanism of the antidepressant-like action of group II mGlu receptor antagonist, MGS0039
por: Pałucha-Poniewiera, Agnieszka, et al.
Publicado: (2010) -
The Antidepressant-like Activity and Cognitive Enhancing Effects of the Combined Administration of (R)-Ketamine and LY341495 in the CUMS Model of Depression in Mice Are Related to the Modulation of Excitatory Synaptic Transmission and LTP in the PFC
por: Pałucha-Poniewiera, Agnieszka, et al.
Publicado: (2023) -
Negative Allosteric Modulators of mGlu(7) Receptor as Putative Antipsychotic Drugs
por: Cieślik, Paulina, et al.
Publicado: (2018) -
Role of Serotonergic System in the Antidepressant Actions of mGlu2/3 Receptor Antagonists: Similarity to Ketamine
por: Chaki, Shigeyuki, et al.
Publicado: (2019)