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Genome-wide analysis of DNA methylation during antagonism of DMOG to MnCl2-induced cytotoxicity in the mouse substantia nigra

Exposure to excessive manganese (Mn) causes manganism, a progressive neurodegenerative disorder similar to idiopathic Parkinson’s disease (IPD). The detailed mechanisms of Mn neurotoxicity in nerve cells, especially in dopaminergic neurons are not yet fully understood. Meanwhile, it is unknown wheth...

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Detalles Bibliográficos
Autores principales: Yang, Nannan, Wei, Yang, Wang, Tan, Guo, Jifeng, Sun, Qiying, Hu, Yacen, Yan, Xinxiang, Zhu, Xiongwei, Tang, Beisha, Xu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933877/
https://www.ncbi.nlm.nih.gov/pubmed/27380887
http://dx.doi.org/10.1038/srep28933