Definition of a Skp2-c-Myc Pathway to Expand Human Beta-cells

Type 2 diabetes (T2D) is characterized by insulin resistance and reduced functional β-cell mass. Developmental differences, failure of adaptive expansion and loss of β-cells via β-cell death or de-differentiation have emerged as the possible causes of this reduced β-cell mass. We hypothesized that t...

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Detalles Bibliográficos
Autores principales: Tiwari, Shiwani, Roel, Chris, Tanwir, Mansoor, Wills, Rachel, Perianayagam, Nidhi, Wang, Peng, Fiaschi-Taesch, Nathalie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933882/
https://www.ncbi.nlm.nih.gov/pubmed/27380896
http://dx.doi.org/10.1038/srep28461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933882/
https://www.ncbi.nlm.nih.gov/pubmed/27380896
http://dx.doi.org/10.1038/srep28461

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