Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling

Curcumin has been shown to possess strong anti-inflammatory activity in many diseases. It has been demonstrated that the janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) cascade and the NAcht leucine-rich-repeat protein 1 (NALP1) inflammasome are important for the syn...

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Detalles Bibliográficos
Autores principales: Liu, Shenbin, Li, Qian, Zhang, Meng-Ting, Mao-Ying, Qi-Liang, Hu, Lang-Yue, Wu, Gen-Cheng, Mi, Wen-Li, Wang, Yan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933926/
https://www.ncbi.nlm.nih.gov/pubmed/27381056
http://dx.doi.org/10.1038/srep28956

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