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Mutations in the G-domain of Ski7 cause specific dysfunction in non-stop decay
Ski7 functions as a cofactor in both normal mRNA turnover and non-stop mRNA decay (NSD) mRNA surveillance in budding yeast. The N-terminal region of Ski7 (Ski7(N)) interacts with the ski-complex and the exosome. The C-terminal region of Ski7 (Ski7(C)) binds guanine nucleotides and shares overall seq...
Autores principales: | Horikawa, Wataru, Endo, Kei, Wada, Miki, Ito, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933942/ https://www.ncbi.nlm.nih.gov/pubmed/27381255 http://dx.doi.org/10.1038/srep29295 |
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