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Impaired neurodevelopment by the low complexity domain of CPEB4 reveals a convergent pathway with neurodegeneration
CPEB4 is an RNA binding protein expressed in neuronal tissues including brain and spinal cord. CPEB4 has two domains: one that is structured for RNA binding and one that is unstructured and low complexity that has no known function. Unstructured low complexity domains (LCDs) in proteins are often fo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933966/ https://www.ncbi.nlm.nih.gov/pubmed/27381259 http://dx.doi.org/10.1038/srep29395 |