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Conformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation

Helix α9 of Bax protein can dimerize in the mitochondrial outer membrane (MOM) and lead to apoptotic pores. However, it remains unclear how different conformations of the dimer contribute to the pore formation on the molecular level. Thus we have investigated various conformational states of the α9...

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Detalles Bibliográficos
Autores principales:	Liao, Chenyi, Zhang, Zhi, Kale, Justin, Andrews, David W., Lin, Jialing, Li, Jianing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933972/ https://www.ncbi.nlm.nih.gov/pubmed/27381287 http://dx.doi.org/10.1038/srep29502

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