Enhancers reside in a unique epigenetic environment during early zebrafish development

BACKGROUND: Enhancers, not promoters, are the most dynamic in their DNA methylation status throughout development and differentiation. Generally speaking, enhancers that are primed to or actually drive gene expression are characterized by relatively low levels of DNA methylation (hypo-methylation),...

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Detalles Bibliográficos
Autores principales: Kaaij, Lucas J. T., Mokry, Michal, Zhou, Meng, Musheev, Michael, Geeven, Geert, Melquiond, Adrien S. J., de Jesus Domingues, António M., de Laat, Wouter, Niehrs, Christof, Smith, Andrew D., Ketting, René F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934011/
https://www.ncbi.nlm.nih.gov/pubmed/27381023
http://dx.doi.org/10.1186/s13059-016-1013-1

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