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Ligation-free ribosome profiling of cell type-specific translation in the brain
Ribosome profiling has emerged as a powerful tool for genome-wide measurements of translation, but library construction requires multiple ligation steps and remains cumbersome relative to more conventional deep-sequencing experiments. We report a new, ligation-free approach to ribosome profiling tha...
Autores principales: | Hornstein, Nicholas, Torres, Daniela, Das Sharma, Sohani, Tang, Guomei, Canoll, Peter, Sims, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934013/ https://www.ncbi.nlm.nih.gov/pubmed/27380875 http://dx.doi.org/10.1186/s13059-016-1005-1 |
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