PreFRP: Prediction and visualization of fluctuation residues in proteins

AIM: The PreFRP web server extracts sequence and basic information of a protein structure and groups amino acid residues in a protein into three important types such as high, moderate, and weak fluctuating residues. MATERIALS AND METHODS: The server takes a protein data bank file or an amino acid sequence as input and prints the probability of amino acid residues to fluctuate. The server also provides a link to Jmol, a molecular visualization program to visualize the high, moderate, and weak fluctuating residues in three different colors. RESULTS: Prediction and visualization of fluctuating amino acid residues in proteins may help to understand the complex three-dimensional structure of proteins and may further help in docking and mutation experiments. AVAILABILITY: The web server is freely accessible through the web page of the author's institution http://www.mpi.edu.in/prefrp/link.html.