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Learning Lessons from Adverse Drug Reactions in Children
Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults. At least one in 500 children will experience an adverse drug reaction each year. For children in hospital, the risk is far grea...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934475/ https://www.ncbi.nlm.nih.gov/pubmed/27417239 http://dx.doi.org/10.3390/children3010001 |
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author | Sammons, Helen M. Choonara, Imti |
author_facet | Sammons, Helen M. Choonara, Imti |
author_sort | Sammons, Helen M. |
collection | PubMed |
description | Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults. At least one in 500 children will experience an adverse drug reaction each year. For children in hospital, the risk is far greater (one in ten). Additionally, different and sometimes unique adverse drug reactions are seen in the paediatric age groups. Some of the major cases of drug toxicity historically have occurred in neonates. It is important that we understand the mechanism of action of adverse drug reactions. Greater understanding alongside rational prescribing should hopefully reduce drug toxicity in children in the future. |
format | Online Article Text |
id | pubmed-4934475 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-49344752016-07-12 Learning Lessons from Adverse Drug Reactions in Children Sammons, Helen M. Choonara, Imti Children (Basel) Review Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults. At least one in 500 children will experience an adverse drug reaction each year. For children in hospital, the risk is far greater (one in ten). Additionally, different and sometimes unique adverse drug reactions are seen in the paediatric age groups. Some of the major cases of drug toxicity historically have occurred in neonates. It is important that we understand the mechanism of action of adverse drug reactions. Greater understanding alongside rational prescribing should hopefully reduce drug toxicity in children in the future. MDPI 2016-01-08 /pmc/articles/PMC4934475/ /pubmed/27417239 http://dx.doi.org/10.3390/children3010001 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sammons, Helen M. Choonara, Imti Learning Lessons from Adverse Drug Reactions in Children |
title | Learning Lessons from Adverse Drug Reactions in Children |
title_full | Learning Lessons from Adverse Drug Reactions in Children |
title_fullStr | Learning Lessons from Adverse Drug Reactions in Children |
title_full_unstemmed | Learning Lessons from Adverse Drug Reactions in Children |
title_short | Learning Lessons from Adverse Drug Reactions in Children |
title_sort | learning lessons from adverse drug reactions in children |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934475/ https://www.ncbi.nlm.nih.gov/pubmed/27417239 http://dx.doi.org/10.3390/children3010001 |
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