Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation

Tau proteins are abnormally aggregated in a range of neurodegenerative tauopathies including Alzheimer’s disease (AD). Recently, tau has emerged as an extensively post-translationally modified protein, among which lysine acetylation is critical for normal tau function and its pathological aggregatio...

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Detalles Bibliográficos
Autores principales: Cohen, Todd J., Constance, Brian H., Hwang, Andrew W., James, Michael, Yuan, Chao-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934699/
https://www.ncbi.nlm.nih.gov/pubmed/27383765
http://dx.doi.org/10.1371/journal.pone.0158470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934699/
https://www.ncbi.nlm.nih.gov/pubmed/27383765
http://dx.doi.org/10.1371/journal.pone.0158470

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