Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells

Elevated serum interleukin-6 (IL-6) levels correlates with tumor grade and poor prognosis in cancer patients. IL-6 has been shown to promote tumor lymphangiogenesis through vascular endothelial growth factor-C (VEGF-C) induction in tumor cells. We recently showed that IL-6 also induced VEGF-C expres...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Han, Yang, Hung-Yu, Huang, Shiu-Wen, Ou, George, Hsu, Ya-Fen, Hsu, Ming-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934912/
https://www.ncbi.nlm.nih.gov/pubmed/27383632
http://dx.doi.org/10.1371/journal.pone.0158839

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