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Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats
BACKGROUND AND AIMS: Although the beneficial effects of statins on stroke have been widely demonstrated both in experimental studies and in clinical trials, the aim of this study is to prepare and characterize a new liposomal delivery system that encapsulates simvastatin to improve its delivery into...
Autores principales: | Campos-Martorell, Mireia, Cano-Sarabia, Mary, Simats, Alba, Hernández-Guillamon, Mar, Rosell, Anna, Maspoch, Daniel, Montaner, Joan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935044/ https://www.ncbi.nlm.nih.gov/pubmed/27418824 http://dx.doi.org/10.2147/IJN.S107292 |
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