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Building for the future: essential infrastructure for rodent ageing studies
When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935732/ https://www.ncbi.nlm.nih.gov/pubmed/27221665 http://dx.doi.org/10.1007/s00335-016-9646-7 |
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author | Wells, Sara E Bellantuono, Ilaria |
author_facet | Wells, Sara E Bellantuono, Ilaria |
author_sort | Wells, Sara E |
collection | PubMed |
description | When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed for several years. Although these issues are not unique to this discipline, the longevity of experiments and indeed the animals, requires a high level of consistency and sustainability to be maintained throughout lengthy periods of time. Moreover, the need to access aged stock or material for more immediate experiments poses many issues for the completion of pilot studies and/or short term intervention studies on older models. In this article, we highlight the increasing demand for ageing research, the resources and infrastructure involved, and the need for large-scale collaborative programmes to advance studies in both a timely and a cost-effective way. |
format | Online Article Text |
id | pubmed-4935732 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-49357322016-07-18 Building for the future: essential infrastructure for rodent ageing studies Wells, Sara E Bellantuono, Ilaria Mamm Genome Article When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed for several years. Although these issues are not unique to this discipline, the longevity of experiments and indeed the animals, requires a high level of consistency and sustainability to be maintained throughout lengthy periods of time. Moreover, the need to access aged stock or material for more immediate experiments poses many issues for the completion of pilot studies and/or short term intervention studies on older models. In this article, we highlight the increasing demand for ageing research, the resources and infrastructure involved, and the need for large-scale collaborative programmes to advance studies in both a timely and a cost-effective way. Springer US 2016-05-24 2016 /pmc/articles/PMC4935732/ /pubmed/27221665 http://dx.doi.org/10.1007/s00335-016-9646-7 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Article Wells, Sara E Bellantuono, Ilaria Building for the future: essential infrastructure for rodent ageing studies |
title | Building for the future: essential infrastructure for rodent ageing studies |
title_full | Building for the future: essential infrastructure for rodent ageing studies |
title_fullStr | Building for the future: essential infrastructure for rodent ageing studies |
title_full_unstemmed | Building for the future: essential infrastructure for rodent ageing studies |
title_short | Building for the future: essential infrastructure for rodent ageing studies |
title_sort | building for the future: essential infrastructure for rodent ageing studies |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935732/ https://www.ncbi.nlm.nih.gov/pubmed/27221665 http://dx.doi.org/10.1007/s00335-016-9646-7 |
work_keys_str_mv | AT wellssarae buildingforthefutureessentialinfrastructureforrodentageingstudies AT bellantuonoilaria buildingforthefutureessentialinfrastructureforrodentageingstudies |