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Building for the future: essential infrastructure for rodent ageing studies

When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed...

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Detalles Bibliográficos
Autores principales: Wells, Sara E, Bellantuono, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935732/
https://www.ncbi.nlm.nih.gov/pubmed/27221665
http://dx.doi.org/10.1007/s00335-016-9646-7
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author Wells, Sara E
Bellantuono, Ilaria
author_facet Wells, Sara E
Bellantuono, Ilaria
author_sort Wells, Sara E
collection PubMed
description When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed for several years. Although these issues are not unique to this discipline, the longevity of experiments and indeed the animals, requires a high level of consistency and sustainability to be maintained throughout lengthy periods of time. Moreover, the need to access aged stock or material for more immediate experiments poses many issues for the completion of pilot studies and/or short term intervention studies on older models. In this article, we highlight the increasing demand for ageing research, the resources and infrastructure involved, and the need for large-scale collaborative programmes to advance studies in both a timely and a cost-effective way.
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spelling pubmed-49357322016-07-18 Building for the future: essential infrastructure for rodent ageing studies Wells, Sara E Bellantuono, Ilaria Mamm Genome Article When planning ageing research using rodent models, the logistics of supply, long term housing and infrastructure provision are important factors to take into consideration. These issues need to be prioritised to ensure they meet the requirements of experiments which potentially will not be completed for several years. Although these issues are not unique to this discipline, the longevity of experiments and indeed the animals, requires a high level of consistency and sustainability to be maintained throughout lengthy periods of time. Moreover, the need to access aged stock or material for more immediate experiments poses many issues for the completion of pilot studies and/or short term intervention studies on older models. In this article, we highlight the increasing demand for ageing research, the resources and infrastructure involved, and the need for large-scale collaborative programmes to advance studies in both a timely and a cost-effective way. Springer US 2016-05-24 2016 /pmc/articles/PMC4935732/ /pubmed/27221665 http://dx.doi.org/10.1007/s00335-016-9646-7 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Wells, Sara E
Bellantuono, Ilaria
Building for the future: essential infrastructure for rodent ageing studies
title Building for the future: essential infrastructure for rodent ageing studies
title_full Building for the future: essential infrastructure for rodent ageing studies
title_fullStr Building for the future: essential infrastructure for rodent ageing studies
title_full_unstemmed Building for the future: essential infrastructure for rodent ageing studies
title_short Building for the future: essential infrastructure for rodent ageing studies
title_sort building for the future: essential infrastructure for rodent ageing studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935732/
https://www.ncbi.nlm.nih.gov/pubmed/27221665
http://dx.doi.org/10.1007/s00335-016-9646-7
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