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Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
5-Nor stemmadenine alkaloids, isolated from the genus Tabernaemontana, display a range of bioactivity. 16-Hydroxy-16,22-dihydroapparicine, the active component of an extract from the Tabernaemontana sp. (dichotoma, elegans, and divaricate), exhibited potent antimalarial activity, representing the fi...
Autores principales: | Noguchi, Yoshihiko, Hirose, Tomoyasu, Ishiyama, Aki, Iwatsuki, Masato, Otoguro, Kazuhiko, Sunazuka, Toshiaki, Ōmura, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935745/ https://www.ncbi.nlm.nih.gov/pubmed/27324906 http://dx.doi.org/10.1007/s11418-016-1012-2 |
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