Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity

We earlier established that nitric oxide (NO) is protective against severe malaria and that arginine and NO levels are reduced in malaria patients. We now show that an M2-like blood monocyte phenotype is significantly associated with hypoargininemia, NO insufficiency, and disease severity in Tanzani...

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Detalles Bibliográficos
Autores principales: Weinberg, J. Brice, Volkheimer, Alicia D., Rubach, Matthew P., Florence, Salvatore M., Mukemba, Jackson P., Kalingonji, Ayam R., Langelier, Charles, Chen, Youwei, Bush, Margaret, Yeo, Tsin W., Granger, Donald L., Anstey, Nicholas M., Mwaikambo, Esther D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935839/
https://www.ncbi.nlm.nih.gov/pubmed/27385484
http://dx.doi.org/10.1038/srep29151

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