A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

Trans-lesion synthesis (TLS) is an important DNA-damage tolerance mechanism that permits ongoing DNA synthesis in cells harbouring damaged genomes. The E3 ubiquitin ligase RAD18 activates TLS by promoting recruitment of Y-family DNA polymerases to sites of DNA-damage-induced replication fork stallin...

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Detalles Bibliográficos
Autores principales: Gao, Yanzhe, Mutter-Rottmayer, Elizabeth, Greenwalt, Alicia M., Goldfarb, Dennis, Yan, Feng, Yang, Yang, Martinez-Chacin, Raquel C., Pearce, Kenneth H., Tateishi, Satoshi, Major, Michael B., Vaziri, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935975/
https://www.ncbi.nlm.nih.gov/pubmed/27377895
http://dx.doi.org/10.1038/ncomms12105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935975/
https://www.ncbi.nlm.nih.gov/pubmed/27377895
http://dx.doi.org/10.1038/ncomms12105

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