Arabidopsis thaliana extracts optimized for polyphenols production as potential therapeutics for the APOE-modulated neuroinflammation characteristic of Alzheimer’s disease in vitro

Although the cause of Alzheimer’s disease (AD) is unknown, glial-induced neuroinflammation is an early symptom. Familial AD is caused by increases in amyloid-beta (Aβ) peptide, particularly soluble oligomeric (oAβ), considered a proximal neurotoxin and neuroinflammatory stimuli. APOE4, a naturally o...

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Detalles Bibliográficos
Autores principales: Ghura, Shivesh, Tai, Leon, Zhao, Ming, Collins, Nicole, Che, Chun-Tao, Warpeha, Katherine M., LaDu, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935988/
https://www.ncbi.nlm.nih.gov/pubmed/27383500
http://dx.doi.org/10.1038/srep29364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935988/
https://www.ncbi.nlm.nih.gov/pubmed/27383500
http://dx.doi.org/10.1038/srep29364

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