H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis

BACKGROUND: Epigenetic changes (i.e., chromatin modifications) occur during chondrogenesis and in osteoarthritis (OA). We investigated the effect of H3K27me3 demethylase inhibition on chondrogenesis and assessed its utility in cartilage tissue engineering and in understanding cartilage destruction i...

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Detalles Bibliográficos
Autores principales: Yapp, Clarence, Carr, Andrew J., Price, Andrew, Oppermann, Udo, Snelling, Sarah J. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936015/
https://www.ncbi.nlm.nih.gov/pubmed/27388528
http://dx.doi.org/10.1186/s13075-016-1053-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936015/
https://www.ncbi.nlm.nih.gov/pubmed/27388528
http://dx.doi.org/10.1186/s13075-016-1053-7

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