Targeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer’s disease patients: application of a second-generation encapsulated cell biodelivery device

BACKGROUND: Targeted delivery of nerve growth factor (NGF) has emerged as a potential therapy for Alzheimer’s disease (AD) due to its regenerative effects on basal forebrain cholinergic neurons. This hypothesis has been tested in patients with AD using encapsulated cell biodelivery of NGF (NGF-ECB)...

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Detalles Bibliográficos
Autores principales: Eyjolfsdottir, Helga, Eriksdotter, Maria, Linderoth, Bengt, Lind, Göran, Juliusson, Bengt, Kusk, Philip, Almkvist, Ove, Andreasen, Niels, Blennow, Kaj, Ferreira, Daniel, Westman, Eric, Nennesmo, Inger, Karami, Azadeh, Darreh-Shori, Taher, Kadir, Ahmadul, Nordberg, Agneta, Sundström, Erik, Wahlund, Lars-Olof, Wall, Anders, Wiberg, Maria, Winblad, Bengt, Seiger, Åke, Wahlberg, Lars, Almqvist, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936020/
https://www.ncbi.nlm.nih.gov/pubmed/27389402
http://dx.doi.org/10.1186/s13195-016-0195-9

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