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Epigenetic silencing of serine protease HTRA1 drives polyploidy

BACKGROUND: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observed characteristics of cancer cells. While some aspects of these events and the checkpoint mechanisms are well studied, not all players have yet been identif...

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Detalles Bibliográficos
Autores principales:	Schmidt, Nina, Irle, Inga, Ripkens, Kamilla, Lux, Vanda, Nelles, Jasmin, Johannes, Christian, Parry, Lee, Greenow, Kirsty, Amir, Sarah, Campioni, Mara, Baldi, Alfonso, Oka, Chio, Kawaichi, Masashi, Clarke, Alan R., Ehrmann, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936022/ https://www.ncbi.nlm.nih.gov/pubmed/27388476 http://dx.doi.org/10.1186/s12885-016-2425-8

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