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Tumor-suppressive effects of atelocollagen-conjugated hsa-miR-520d-5p on un-differentiated cancer cells in a mouse xenograft model
BACKGROUND: We previously demonstrated that hsa-miR-520d-5p can convert cancer cells into induced pluripotent stem cells (iPSCs) or mesenchymal stem cells (MSCs) via a demethylation process and p53 upregulation in vivo. Additionally, we have reported the non-tumorigenic effect of miR-520d-5p on norm...
Autores principales: | Ishihara, Yoshitaka, Tsuno, Satoshi, Kuwamoto, Satoshi, Yamashita, Taro, Endo, Yusuke, Miura, Keigo, Miura, Yugo, Sato, Takemasa, Hasegawa, Junichi, Miura, Norimasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936056/ https://www.ncbi.nlm.nih.gov/pubmed/27388711 http://dx.doi.org/10.1186/s12885-016-2467-y |
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