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Tumor-suppressive effects of atelocollagen-conjugated hsa-miR-520d-5p on un-differentiated cancer cells in a mouse xenograft model

BACKGROUND: We previously demonstrated that hsa-miR-520d-5p can convert cancer cells into induced pluripotent stem cells (iPSCs) or mesenchymal stem cells (MSCs) via a demethylation process and p53 upregulation in vivo. Additionally, we have reported the non-tumorigenic effect of miR-520d-5p on norm...

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Detalles Bibliográficos
Autores principales: Ishihara, Yoshitaka, Tsuno, Satoshi, Kuwamoto, Satoshi, Yamashita, Taro, Endo, Yusuke, Miura, Keigo, Miura, Yugo, Sato, Takemasa, Hasegawa, Junichi, Miura, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936056/
https://www.ncbi.nlm.nih.gov/pubmed/27388711
http://dx.doi.org/10.1186/s12885-016-2467-y

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