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Depletion of Alveolar Macrophages Does Not Prevent Hantavirus Disease Pathogenesis in Golden Syrian Hamsters

Andes virus (ANDV) is associated with a lethal vascular leak syndrome in humans termed hantavirus pulmonary syndrome (HPS). The mechanism for the massive vascular leakage associated with HPS is poorly understood; however, dysregulation of components of the immune response is often suggested as a pos...

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Detalles Bibliográficos
Autores principales: Hammerbeck, Christopher D., Brocato, Rebecca L., Bell, Todd M., Schellhase, Christopher W., Mraz, Steven R., Queen, Laurie A., Hooper, Jay W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936146/
https://www.ncbi.nlm.nih.gov/pubmed/27099308
http://dx.doi.org/10.1128/JVI.00304-16