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Classical V600E and other non-hotspot BRAF mutations in adult differentiated thyroid cancer

BACKGROUND: BRAF is the most frequently mutated gene in differentiated thyroid cancer (DTC). Previous studies on DTC have well documented high rates of the BRAF(V600E) mutation in patients of mixed ages. Previous studies either included a mix of pediatric and adult patients or pediatric patients onl...

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Detalles Bibliográficos
Autores principales: Murugan, Avaniyapuram Kannan, Qasem, Ebtesam, Al-Hindi, Hindi, Shi, Yufei, Alzahrani, Ali S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936197/
https://www.ncbi.nlm.nih.gov/pubmed/27387551
http://dx.doi.org/10.1186/s12967-016-0958-x