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Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer

BACKGROUND: Diabetic foot ulceration is receiving more attention because of its high amputation and mortality rate. It is essential to establish the frequency of amputations in people with diabetes after any change to the management of diabetic foot care. The present study aim to compare the frequen...

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Autores principales: Wang, Chuan, Mai, Lifang, Yang, Chuan, Liu, Dan, Sun, Kan, Song, Weidong, Luo, Baoming, Li, Yan, Xu, Mingtong, Zhang, Shaoling, Li, Fangping, Ren, Meng, Yan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936325/
https://www.ncbi.nlm.nih.gov/pubmed/27388440
http://dx.doi.org/10.1186/s12902-016-0111-0
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author Wang, Chuan
Mai, Lifang
Yang, Chuan
Liu, Dan
Sun, Kan
Song, Weidong
Luo, Baoming
Li, Yan
Xu, Mingtong
Zhang, Shaoling
Li, Fangping
Ren, Meng
Yan, Li
author_facet Wang, Chuan
Mai, Lifang
Yang, Chuan
Liu, Dan
Sun, Kan
Song, Weidong
Luo, Baoming
Li, Yan
Xu, Mingtong
Zhang, Shaoling
Li, Fangping
Ren, Meng
Yan, Li
author_sort Wang, Chuan
collection PubMed
description BACKGROUND: Diabetic foot ulceration is receiving more attention because of its high amputation and mortality rate. It is essential to establish the frequency of amputations in people with diabetes after any change to the management of diabetic foot care. The present study aim to compare the frequency of lower-extremity amputations in patients with diabetes foot ulcer over a ten-year period. METHODS: Six hundred forty eight patients with diabetes foot ulcer were retrospectively studied from 2004 to 2013. The clinical features, laboratory results and the lower-extremity amputations were recorded. Major amputation was defined as amputations above the ankle while minor amputation was amputations below the ankle in the present study. RESULTS: Patients with diabetic foot ulcer were old (age 66.96 ± 11.96 years), with a long duration of diabetes (10.30 ± 6.94 years), high HbA1c (9.19 ± 2.62 %), SBP (144.05 ± 24.18 mmHg), DBP (79.53 ± 11.88 mmHg), LDL-C (2.71 ± 0.93 mmol/L) and had great frequency of neuropathy (62.7 %), retinopathy (45.0 %), nephropathy (39.5 %) and PAD (33.2 %). From 2004 to 2013, the frequency of all lower-extremity amputations is 12.0 % (5.2 % major amputation, 6.8 % minor amputation). The frequency of major amputations decreased from 9.5 % in 2004 and 14.5 % in 2005 to less than 5.0 % after 2006. In particular, there was a significant decline in major amputations of diabetic foot patient with Wagner 3 to 4 wounds. The frequency rate of major amputations in diabetic foot patient with Wagner 3 to 4 wounds fell from 35.7 % in 2004 to 4.4 % after 2007. The change in frequency of minor amputations was fluctuation. CONCLUSION: This study demonstrates that the introduction of a multidisciplinary team, coordinated by an endocrinologist and a podiatrist, for managing diabetic foot disease is associated with a reduction in the frequency of major amputations in patients with diabetes.
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spelling pubmed-49363252016-07-08 Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer Wang, Chuan Mai, Lifang Yang, Chuan Liu, Dan Sun, Kan Song, Weidong Luo, Baoming Li, Yan Xu, Mingtong Zhang, Shaoling Li, Fangping Ren, Meng Yan, Li BMC Endocr Disord Research Article BACKGROUND: Diabetic foot ulceration is receiving more attention because of its high amputation and mortality rate. It is essential to establish the frequency of amputations in people with diabetes after any change to the management of diabetic foot care. The present study aim to compare the frequency of lower-extremity amputations in patients with diabetes foot ulcer over a ten-year period. METHODS: Six hundred forty eight patients with diabetes foot ulcer were retrospectively studied from 2004 to 2013. The clinical features, laboratory results and the lower-extremity amputations were recorded. Major amputation was defined as amputations above the ankle while minor amputation was amputations below the ankle in the present study. RESULTS: Patients with diabetic foot ulcer were old (age 66.96 ± 11.96 years), with a long duration of diabetes (10.30 ± 6.94 years), high HbA1c (9.19 ± 2.62 %), SBP (144.05 ± 24.18 mmHg), DBP (79.53 ± 11.88 mmHg), LDL-C (2.71 ± 0.93 mmol/L) and had great frequency of neuropathy (62.7 %), retinopathy (45.0 %), nephropathy (39.5 %) and PAD (33.2 %). From 2004 to 2013, the frequency of all lower-extremity amputations is 12.0 % (5.2 % major amputation, 6.8 % minor amputation). The frequency of major amputations decreased from 9.5 % in 2004 and 14.5 % in 2005 to less than 5.0 % after 2006. In particular, there was a significant decline in major amputations of diabetic foot patient with Wagner 3 to 4 wounds. The frequency rate of major amputations in diabetic foot patient with Wagner 3 to 4 wounds fell from 35.7 % in 2004 to 4.4 % after 2007. The change in frequency of minor amputations was fluctuation. CONCLUSION: This study demonstrates that the introduction of a multidisciplinary team, coordinated by an endocrinologist and a podiatrist, for managing diabetic foot disease is associated with a reduction in the frequency of major amputations in patients with diabetes. BioMed Central 2016-07-07 /pmc/articles/PMC4936325/ /pubmed/27388440 http://dx.doi.org/10.1186/s12902-016-0111-0 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Wang, Chuan
Mai, Lifang
Yang, Chuan
Liu, Dan
Sun, Kan
Song, Weidong
Luo, Baoming
Li, Yan
Xu, Mingtong
Zhang, Shaoling
Li, Fangping
Ren, Meng
Yan, Li
Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer
title Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer
title_full Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer
title_fullStr Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer
title_full_unstemmed Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer
title_short Reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer
title_sort reducing major lower extremity amputations after the introduction of a multidisciplinary team in patient with diabetes foot ulcer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936325/
https://www.ncbi.nlm.nih.gov/pubmed/27388440
http://dx.doi.org/10.1186/s12902-016-0111-0
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