Risk factors of community-associated infections in Chinese patients with diabetes: A meta-analysis

OBJECTIVE: To identify the common sites and risk factors of community-associated infections in Chinese patients with diabetes. MATERIALS AND METHODS: The Wanfang, CNKI, PUBMED and VIP databases restricting to Chinese patients with diabetes were queried without restriction to time period. Randomized controlled trials (RCTs) on the risk factors of community-associated infections in Chinese patients with diabetes were considered. Polled odd ratios (OR) and 95% confidence intervals (95% CI) were used for each factor in fixed or random-effect meta-analyses. RESULTS: Twelve studies were identified that investigated seven risk factors of community-associated infections in Chinese patients with diabetes. The average infection incidence was 39.55%. The respiratory tract and urology tract were the predilection sites. Meta-analysis results are as follows: Diabetic patients with chronic complications (OR: 1.63; 95% CI 1.45–1.82), advanced age (OR: 1.30; 95% CI 1.19–1.42), longer duration (OR: 1.47; 95% CI 1.35–1.61) or ketoacidosis (OR: 1.37; 95% CI 1.13–1.66) were more prone to suffer from infections. Those with better glycemic control (OR: 0.68; 95% CI 0.61–0.76) or males (OR: 0.69; 95% CI 0.64–0.75) were less prone to suffer from infections. CONCLUSION: Chinese patients with diabetes had a high incidence of community-associated infections. We should highlight the risk factors that might provide a reference for the same.