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Functions of PARylation in DNA Damage Repair Pathways

Protein poly ADP-ribosylation (PARylation) is a widespread post-translational modification at DNA lesions, which is catalyzed by poly(ADP-ribose) polymerases (PARPs). This modification regulates a number of biological processes including chromatin reorganization, DNA damage response (DDR), transcrip...

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Detalles Bibliográficos
Autores principales:	Wei, Huiting, Yu, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936651/ https://www.ncbi.nlm.nih.gov/pubmed/27240471 http://dx.doi.org/10.1016/j.gpb.2016.05.001

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