Bioprinted 3D Primary Liver Tissues Allow Assessment of Organ-Level Response to Clinical Drug Induced Toxicity In Vitro

Modeling clinically relevant tissue responses using cell models poses a significant challenge for drug development, in particular for drug induced liver injury (DILI). This is mainly because existing liver models lack longevity and tissue-level complexity which limits their utility in predictive tox...

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Detalles Bibliográficos
Autores principales: Nguyen, Deborah G., Funk, Juergen, Robbins, Justin B., Crogan-Grundy, Candace, Presnell, Sharon C., Singer, Thomas, Roth, Adrian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936711/
https://www.ncbi.nlm.nih.gov/pubmed/27387377
http://dx.doi.org/10.1371/journal.pone.0158674

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