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Recombinant Tissue Plasminogen Activator Induces Neurological Side Effects Independent on Thrombolysis in Mechanical Animal Models of Focal Cerebral Infarction: A Systematic Review and Meta-Analysis

BACKGROUND AND PURPOSE: Recombinant tissue plasminogen activator (rtPA) is the only effective drug approved by US FDA to treat ischemic stroke, and it contains pleiotropic effects besides thrombolysis. We performed a meta-analysis to clarify effect of tissue plasminogen activator (tPA) on cerebral i...

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Detalles Bibliográficos
Autores principales:	Dong, Mei-Xue, Hu, Qing-Chuan, Shen, Peng, Pan, Jun-Xi, Wei, You-Dong, Liu, Yi-Yun, Ren, Yi-Fei, Liang, Zi-Hong, Wang, Hai-Yang, Zhao, Li-Bo, Xie, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936748/ https://www.ncbi.nlm.nih.gov/pubmed/27387385 http://dx.doi.org/10.1371/journal.pone.0158848

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