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Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids
TRIM5 proteins are restriction factors that block retroviral infections by binding viral capsids and preventing reverse transcription. Capsid recognition is mediated by C-terminal domains on TRIM5α (SPRY) or TRIMCyp (cyclophilin A), which interact weakly with capsids. Efficient capsid recognition al...
Autores principales: | Li, Yen-Li, Chandrasekaran, Viswanathan, Carter, Stephen D, Woodward, Cora L, Christensen, Devin E, Dryden, Kelly A, Pornillos, Owen, Yeager, Mark, Ganser-Pornillos, Barbie K, Jensen, Grant J, Sundquist, Wesley I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936896/ https://www.ncbi.nlm.nih.gov/pubmed/27253068 http://dx.doi.org/10.7554/eLife.16269 |
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