Evaluation of the biological differences of canine and human factor VIII in gene delivery: implications in human hemophilia treatment

The canine is the most important large animal model for testing novel hemophilia A(HA) treatment. It is often necessary to use canine factor VIII (cFIII) gene or protein for the evaluation of HA treatment in the canine model. However, the different biological properties between cFVIII and human FVII...

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Detalles Bibliográficos
Autores principales: Wang, Qizhao, Dong, Biao, Firrman, Jenni, Wu, Wenman, Roberts, Sean, Moore, Andrea Rossi, Liu, LinShu, Chin, Mario P.S., Diao, Yong, Kost, Joseph, Xiao, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936945/
https://www.ncbi.nlm.nih.gov/pubmed/27064790
http://dx.doi.org/10.1038/gt.2016.34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936945/
https://www.ncbi.nlm.nih.gov/pubmed/27064790
http://dx.doi.org/10.1038/gt.2016.34

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