The effect of the immune system on ovarian function and features of ovarian germline stem cells

In addition to its role in maintaining organism homeostasis, the immune system also plays a crucial role in the modulation of ovarian function, as it regulates ovarian development, follicular maturation, ovulation and the formation of the corpus luteum. Ovarian germline stem cells are pluripotent st...

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Detalles Bibliográficos
Autores principales: Ye, Haifeng, Li, Xiaoyan, Zheng, Tuochen, Liang, Xia, Li, Jia, Huang, Jian, Pan, Zezheng, Zheng, Yuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937004/
https://www.ncbi.nlm.nih.gov/pubmed/27398269
http://dx.doi.org/10.1186/s40064-016-2390-3
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author Ye, Haifeng
Li, Xiaoyan
Zheng, Tuochen
Liang, Xia
Li, Jia
Huang, Jian
Pan, Zezheng
Zheng, Yuehui
author_facet Ye, Haifeng
Li, Xiaoyan
Zheng, Tuochen
Liang, Xia
Li, Jia
Huang, Jian
Pan, Zezheng
Zheng, Yuehui
author_sort Ye, Haifeng
collection PubMed
description In addition to its role in maintaining organism homeostasis, the immune system also plays a crucial role in the modulation of ovarian function, as it regulates ovarian development, follicular maturation, ovulation and the formation of the corpus luteum. Ovarian germline stem cells are pluripotent stem cells derived from the ovarian cortex that can differentiate into ovarian germ cells and primary granulosa cells. Recent work has demonstrated that the proliferation and differentiation of ovarian germline stem cells is regulated in part by immune cells and their secreted factors. This paper reviews the role of the immune system in the regulation of ovarian function, the relationship between immune components and ovarian germline stem cells and current research efforts in this field.
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spelling pubmed-49370042016-07-08 The effect of the immune system on ovarian function and features of ovarian germline stem cells Ye, Haifeng Li, Xiaoyan Zheng, Tuochen Liang, Xia Li, Jia Huang, Jian Pan, Zezheng Zheng, Yuehui Springerplus Review In addition to its role in maintaining organism homeostasis, the immune system also plays a crucial role in the modulation of ovarian function, as it regulates ovarian development, follicular maturation, ovulation and the formation of the corpus luteum. Ovarian germline stem cells are pluripotent stem cells derived from the ovarian cortex that can differentiate into ovarian germ cells and primary granulosa cells. Recent work has demonstrated that the proliferation and differentiation of ovarian germline stem cells is regulated in part by immune cells and their secreted factors. This paper reviews the role of the immune system in the regulation of ovarian function, the relationship between immune components and ovarian germline stem cells and current research efforts in this field. Springer International Publishing 2016-07-07 /pmc/articles/PMC4937004/ /pubmed/27398269 http://dx.doi.org/10.1186/s40064-016-2390-3 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Ye, Haifeng
Li, Xiaoyan
Zheng, Tuochen
Liang, Xia
Li, Jia
Huang, Jian
Pan, Zezheng
Zheng, Yuehui
The effect of the immune system on ovarian function and features of ovarian germline stem cells
title The effect of the immune system on ovarian function and features of ovarian germline stem cells
title_full The effect of the immune system on ovarian function and features of ovarian germline stem cells
title_fullStr The effect of the immune system on ovarian function and features of ovarian germline stem cells
title_full_unstemmed The effect of the immune system on ovarian function and features of ovarian germline stem cells
title_short The effect of the immune system on ovarian function and features of ovarian germline stem cells
title_sort effect of the immune system on ovarian function and features of ovarian germline stem cells
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937004/
https://www.ncbi.nlm.nih.gov/pubmed/27398269
http://dx.doi.org/10.1186/s40064-016-2390-3
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