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Adhesions and endometriosis: challenges in subfertility management: (An expert opinion of the ANGEL-The ANti-Adhesions in Gynaecology Expert PaneL-group)

There is molecular evidence that endometriosis has a negative impact on the ovaries, although the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tubo-ovarian unit can be directly by distorting the anatomy, indirectly by invoking inflam...

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Detalles Bibliográficos
Autores principales: De Wilde, R. L., Alvarez, J., Brölmann, H., Campo, R., Cheong, Y., Lundorff, P., Pawelczyk, L., Roman, H., di Spiezio Sardo, A., Wallwiener, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937065/
https://www.ncbi.nlm.nih.gov/pubmed/26894304
http://dx.doi.org/10.1007/s00404-016-4049-2
Descripción
Sumario:There is molecular evidence that endometriosis has a negative impact on the ovaries, although the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tubo-ovarian unit can be directly by distorting the anatomy, indirectly by invoking inflammation or by oxidative damage with poorer-quality oocytes. Endometriosis even seems to have a negative effect on pregnancy outcome after in vitro fertilization.