Cargando…

P2Y6 Receptor-Mediated Microglial Phagocytosis in Radiation-Induced Brain Injury

Microglia are the resident immune cells and the professional phagocytic cells of the CNS, showing a multitude of cellular responses after activation. However, how microglial phagocytosis changes and whether it is involved in radiation-induced brain injury remain unknown. In the current study, we fou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yongteng, Hu, Weihan, Liu, Yimin, Xu, Pengfei, Li, Zichen, Wu, Rong, Shi, Xiaolei, Tang, Yamei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937101/ https://www.ncbi.nlm.nih.gov/pubmed/26099306 http://dx.doi.org/10.1007/s12035-015-9282-3

Ejemplares similares

P2Y6 receptor inhibition aggravates ischemic brain injury by reducing microglial phagocytosis
por: Wen, Ruo‐Xue, et al.
Publicado: (2020)

Effect of edaravone on radiation-induced brain necrosis in patients with nasopharyngeal carcinoma after radiotherapy: a randomized controlled trial
por: Tang, Yamei, et al.
Publicado: (2014)

The Role of Microglial Phagocytosis in Ischemic Stroke
por: Jia, Junqiu, et al.
Publicado: (2022)

Phagocytosis of Microglia in the Central Nervous System Diseases
por: Fu, Ruying, et al.
Publicado: (2014)

Prognostic Value of Nutritional Assessments on Overall Survival in Head and Neck Cancer Survivors with Radiation-Induced Brain Necrosis
por: Pan, Dong, et al.
Publicado: (2023)

Psychological Disorders, Cognitive Dysfunction and Quality of Life in Nasopharyngeal Carcinoma Patients with Radiation-Induced Brain Injury
por: Tang, Yamei, et al.
Publicado: (2012)

P2Y(6) receptor‐dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging
por: Dundee, Jacob M., et al.
Publicado: (2022)

Reticulocalbin-1 Facilitates Microglial Phagocytosis
por: Ding, Ying, et al.
Publicado: (2015)

Bevacizumab Combined with Corticosteroids Does Not Improve the Clinical Outcome of Nasopharyngeal Carcinoma Patients With Radiation-Induced Brain Necrosis
por: Li, Honghong, et al.
Publicado: (2021)

CD22 blockade restores homeostatic microglial phagocytosis in aging brains
por: Pluvinage, John V., et al.
Publicado: (2019)

Neutrophil to lymphocyte ratio as a predictor for treatment of radiation‐induced brain necrosis with bevacizumab in nasopharyngeal carcinoma patients
por: Cai, Jinhua, et al.
Publicado: (2022)

Neurosurgery and prognosis in patients with radiation-induced brain injury after nasopharyngeal carcinoma radiotherapy: a follow-up study
por: Li, Yi, et al.
Publicado: (2013)

Blood–Brain Barrier Repair of Bevacizumab and Corticosteroid as Prediction of Clinical Improvement and Relapse Risk in Radiation-Induced Brain Necrosis: A Retrospective Observational Study
por: Xue, Ruiqi, et al.
Publicado: (2021)

Qki is an essential regulator of microglial phagocytosis in demyelination
por: Ren, Jiangong, et al.
Publicado: (2020)

Absent in melanoma 2 mediates aging‐related cognitive dysfunction by acting on complement‐dependent microglial phagocytosis
por: Ye, Lei, et al.
Publicado: (2023)

Commentary: CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
por: Wei, Penghui, et al.
Publicado: (2019)

Toll-like receptor stimulation increases phagocytosis of Cryptococcus neoformans by microglial cells
por: Redlich, Sandra, et al.
Publicado: (2013)

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
por: Zhao, Lian, et al.
Publicado: (2015)

Alginate-Derived Oligosaccharide Inhibits Neuroinflammation and Promotes Microglial Phagocytosis of β-Amyloid
por: Zhou, Rui, et al.
Publicado: (2015)

Microglial P2Y(6) calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis
por: Umpierre, Anthony D., et al.
Publicado: (2023)

Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8
por: Cai, Xiaoying, et al.
Publicado: (2021)

Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury
por: Zhang, Zhan, et al.
Publicado: (2022)

Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction
por: Konishi, Hiroyuki, et al.
Publicado: (2020)

Interrogation of human microglial phagocytosis by CRISPR genome editing
por: Chang, Jason Cheng-Yu, et al.
Publicado: (2023)

Microglial TREM-1 receptor mediates neuroinflammatory injury via interaction with SYK in experimental ischemic stroke
por: Xu, Pengfei, et al.
Publicado: (2019)

Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells
por: Ferreira, Raquel, et al.
Publicado: (2011)

Astrocytic CXCL5 hinders microglial phagocytosis of myelin debris and aggravates white matter injury in chronic cerebral ischemia
por: Cao, Qian, et al.
Publicado: (2023)

Sphingosine-1-phosphate, a novel TREM2 ligand, promotes microglial phagocytosis to protect against ischemic brain injury
por: Xue, Tengfei, et al.
Publicado: (2022)

Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
por: Abiega, Oihane, et al.
Publicado: (2016)

Sweepers in the CNS: Microglial Migration and Phagocytosis in the Alzheimer Disease Pathogenesis
por: Noda, Mariko, et al.
Publicado: (2012)

MFG-E8 Regulates Microglial Phagocytosis of Apoptotic Neurons
por: Fuller, Abby D., et al.
Publicado: (2008)

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
por: Sierra, Amanda, et al.
Publicado: (2013)

Roles of Microglial Phagocytosis and Inflammatory Mediators in the Pathophysiology of Sleep Disorders
por: Nadjar, Agnes, et al.
Publicado: (2017)

Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets
por: Nizami, Sohaib, et al.
Publicado: (2019)

Microglial Phagocytosis—Rational but Challenging Therapeutic Target in Multiple Sclerosis
por: Pinto, Maria V., et al.
Publicado: (2020)

Central nervous system diseases related to pathological microglial phagocytosis
por: Wang, Ke, et al.
Publicado: (2021)

Metabolic regulation of microglial phagocytosis: Implications for Alzheimer's disease therapeutics
por: Lepiarz-Raba, Izabela, et al.
Publicado: (2023)

The P2X(7) Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis
por: Campagno, Keith E., et al.
Publicado: (2021)

Correction: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
por: Abiega, Oihane, et al.
Publicado: (2016)

Correction: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
por: Abiega, Oihane, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ddkgtnncmugsa3g0ve260gqlpf