Dysfunction of the Voltage‐Gated K(+) Channel β2 Subunit in a Familial Case of Brugada Syndrome

BACKGROUND: The Brugada syndrome is an inherited cardiac arrhythmia associated with high risk of sudden death. Although 20% of patients with Brugada syndrome carry mutations in SCN5A, the molecular mechanisms underlying this condition are still largely unknown. METHODS AND RESULTS: We combined whole...

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Detalles Bibliográficos
Autores principales: Portero, Vincent, Le Scouarnec, Solena, Es‐Salah‐Lamoureux, Zeineb, Burel, Sophie, Gourraud, Jean‐Baptiste, Bonnaud, Stéphanie, Lindenbaum, Pierre, Simonet, Floriane, Violleau, Jade, Baron, Estelle, Moreau, Eléonore, Scott, Carol, Chatel, Stéphanie, Loussouarn, Gildas, O'Hara, Thomas, Mabo, Philippe, Dina, Christian, Le Marec, Hervé, Schott, Jean‐Jacques, Probst, Vincent, Baró, Isabelle, Marionneau, Céline, Charpentier, Flavien, Redon, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937261/
https://www.ncbi.nlm.nih.gov/pubmed/27287695
http://dx.doi.org/10.1161/JAHA.115.003122

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