Monosialoganglioside‐Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins

BACKGROUND: Light chain amyloidosis (AL) is associated with high mortality, especially in patients with advanced cardiovascular involvement. It is caused by toxicity of misfolded light chain proteins (LC) in vascular, cardiac, and other tissues. There is no treatment to reverse LC tissue toxicity. W...

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Detalles Bibliográficos
Autores principales: Franco, Daniel A., Truran, Seth, Weissig, Volkmar, Guzman‐Villanueva, Diana, Karamanova, Nina, Senapati, Subhadip, Burciu, Camelia, Ramirez‐Alvarado, Marina, Blancas‐Mejia, Luis M., Lindsay, Stuart, Hari, Parameswaran, Migrino, Raymond Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937272/
https://www.ncbi.nlm.nih.gov/pubmed/27412900
http://dx.doi.org/10.1161/JAHA.116.003318

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