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Postnatal Development of Right Ventricular Myofibrillar Biomechanics in Relation to the Sarcomeric Protein Phenotype in Pediatric Patients with Conotruncal Heart Defects

BACKGROUND: The postnatal development of myofibrillar mechanics, a major determinant of heart function, is unknown in pediatric patients with tetralogy of Fallot and related structural heart defects. We therefore determined the mechanical properties of myofibrils isolated from right ventricular tiss...

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Detalles Bibliográficos
Autores principales: Elhamine, Fatiha, Iorga, Bogdan, Krüger, Martina, Hunger, Mona, Eckhardt, Jan, Sreeram, Narayanswami, Bennink, Gerardus, Brockmeier, Konrad, Pfitzer, Gabriele, Stehle, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937289/
https://www.ncbi.nlm.nih.gov/pubmed/27353610
http://dx.doi.org/10.1161/JAHA.116.003699