Cargando…
Repurposing the CRISPR-Cas9 system for targeted DNA methylation
Epigenetic studies relied so far on correlations between epigenetic marks and gene expression pattern. Technologies developed for epigenome editing now enable direct study of functional relevance of precise epigenetic modifications and gene regulation. The reversible nature of epigenetic modificatio...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937303/ https://www.ncbi.nlm.nih.gov/pubmed/26969735 http://dx.doi.org/10.1093/nar/gkw159 |