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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination

We examined the influence of the tetratricopeptide repeat factor XAB2 on chromosomal break repair, and found that XAB2 promotes end resection that generates the 3′ ssDNA intermediate for homologous recombination (HR). Namely, XAB2 is important for chromosomal double-strand break (DSB) repair via two...

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Detalles Bibliográficos
Autores principales:	Onyango, David O., Howard, Sean M., Neherin, Kashfia, Yanez, Diana A., Stark, Jeremy M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937314/ https://www.ncbi.nlm.nih.gov/pubmed/27084940 http://dx.doi.org/10.1093/nar/gkw275

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