Poly(A)-binding proteins are required for microRNA-mediated silencing and to promote target deadenylation in C. elegans

Cytoplasmic poly(A)-binding proteins (PABPs) link mRNA 3′ termini to translation initiation factors, but they also play key roles in mRNA regulation and decay. Reports from mice, zebrafish and Drosophila further involved PABPs in microRNA (miRNA)-mediated silencing, but through seemingly distinct me...

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Detalles Bibliográficos
Autores principales: Flamand, Mathieu N., Wu, Edlyn, Vashisht, Ajay, Jannot, Guillaume, Keiper, Brett D., Simard, Martin J., Wohlschlegel, James, Duchaine, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937315/
https://www.ncbi.nlm.nih.gov/pubmed/27095199
http://dx.doi.org/10.1093/nar/gkw276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937315/
https://www.ncbi.nlm.nih.gov/pubmed/27095199
http://dx.doi.org/10.1093/nar/gkw276

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