Mitochondrial transcription termination factor 1 directs polar replication fork pausing

During replication of nuclear ribosomal DNA (rDNA), clashes with the transcription apparatus can cause replication fork collapse and genomic instability. To avoid this problem, a replication fork barrier protein is situated downstream of rDNA, there preventing replication in the direction opposite r...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Yonghong, Posse, Viktor, Zhu, Xuefeng, Hyvärinen, Anne K., Jacobs, Howard T., Falkenberg, Maria, Gustafsson, Claes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937320/
https://www.ncbi.nlm.nih.gov/pubmed/27112570
http://dx.doi.org/10.1093/nar/gkw302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937320/
https://www.ncbi.nlm.nih.gov/pubmed/27112570
http://dx.doi.org/10.1093/nar/gkw302

Ejemplares similares