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Mitochondrial transcription termination factor 1 directs polar replication fork pausing

During replication of nuclear ribosomal DNA (rDNA), clashes with the transcription apparatus can cause replication fork collapse and genomic instability. To avoid this problem, a replication fork barrier protein is situated downstream of rDNA, there preventing replication in the direction opposite r...

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Detalles Bibliográficos
Autores principales:	Shi, Yonghong, Posse, Viktor, Zhu, Xuefeng, Hyvärinen, Anne K., Jacobs, Howard T., Falkenberg, Maria, Gustafsson, Claes M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937320/ https://www.ncbi.nlm.nih.gov/pubmed/27112570 http://dx.doi.org/10.1093/nar/gkw302

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