Dynamic binding of replication protein a is required for DNA repair

Replication protein A (RPA), the major eukaryotic single-stranded DNA (ssDNA) binding protein, is essential for replication, repair and recombination. High-affinity ssDNA-binding by RPA depends on two DNA binding domains in the large subunit of RPA. Mutation of the evolutionarily conserved aromatic...

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Detalles Bibliográficos
Autores principales: Chen, Ran, Subramanyam, Shyamal, Elcock, Adrian H., Spies, Maria, Wold, Marc S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937323/
https://www.ncbi.nlm.nih.gov/pubmed/27131385
http://dx.doi.org/10.1093/nar/gkw339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937323/
https://www.ncbi.nlm.nih.gov/pubmed/27131385
http://dx.doi.org/10.1093/nar/gkw339

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