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Dynamic binding of replication protein a is required for DNA repair

Replication protein A (RPA), the major eukaryotic single-stranded DNA (ssDNA) binding protein, is essential for replication, repair and recombination. High-affinity ssDNA-binding by RPA depends on two DNA binding domains in the large subunit of RPA. Mutation of the evolutionarily conserved aromatic...

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Detalles Bibliográficos
Autores principales:	Chen, Ran, Subramanyam, Shyamal, Elcock, Adrian H., Spies, Maria, Wold, Marc S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937323/ https://www.ncbi.nlm.nih.gov/pubmed/27131385 http://dx.doi.org/10.1093/nar/gkw339

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