Cargando…
Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells
Predictive toxicology using stem cells or their derived tissues has gained increasing importance in biomedical and pharmaceutical research. Here, we show that toxicity category prediction by support vector machines (SVMs), which uses qRT-PCR data from 20 categorized chemicals based on a human embryo...
Autores principales: | Yamane, Junko, Aburatani, Sachiyo, Imanishi, Satoshi, Akanuma, Hiromi, Nagano, Reiko, Kato, Tsuyoshi, Sone, Hideko, Ohsako, Seiichiroh, Fujibuchi, Wataru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937330/ https://www.ncbi.nlm.nih.gov/pubmed/27207879 http://dx.doi.org/10.1093/nar/gkw450 |
Ejemplares similares
-
Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells
por: Yamane, Junko, et al.
Publicado: (2019) -
Multi-Parametric Profiling Network Based on Gene Expression and Phenotype Data: A Novel Approach to Developmental Neurotoxicity Testing
por: Nagano, Reiko, et al.
Publicado: (2011) -
Identification of Stage-Specific Gene Expression Signatures in Response to Retinoic Acid during the Neural Differentiation of Mouse Embryonic Stem Cells
por: Akanuma, Hiromi, et al.
Publicado: (2012) -
Tyroxine Hydroxylase-Positive Neuronal Cell Population is Increased by Temporal Dioxin Exposure at Early Stage of Differentiation from Human Embryonic Stem Cells
por: Sarma, Sailendra Nath, et al.
Publicado: (2019) -
Does the prenatal bisphenol A exposure alter DNA methylation levels in the mouse hippocampus?: An analysis using a high-sensitivity methylome technique
por: Aiba, Toshiki, et al.
Publicado: (2018)