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Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system

Shewanella putrefaciens CN-32 contains a single Type I-Fv CRISPR-Cas system which confers adaptive immunity against bacteriophage infection. Three Cas proteins (Cas6f, Cas7fv, Cas5fv) and mature CRISPR RNAs were shown to be required for the assembly of an interference complex termed Cascade. The Cas...

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Detalles Bibliográficos
Autores principales:	Gleditzsch, Daniel, Müller-Esparza, Hanna, Pausch, Patrick, Sharma, Kundan, Dwarakanath, Srivatsa, Urlaub, Henning, Bange, Gert, Randau, Lennart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937334/ https://www.ncbi.nlm.nih.gov/pubmed/27216815 http://dx.doi.org/10.1093/nar/gkw469

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